brain natriuretic peptide as a novel diagnostic biomarker in kawasaki disease

نویسندگان

kazunari kaneko department of pediatrics, kansai medical university, osaka, japan; department of pediatrics, kansai medical university, 2-5-1 shin-machi, hirakata-shi, p.o. box: 573-1010, osaka, japan. tel: +81-728040101-ext. 2560, fax: +81-728042758

ken yoshimura department of pediatrics, kansai medical university, osaka, japanسازمان اصلی تایید شده: 0 موسسات و مراکز خارج از کشور

shoji tsuji department of pediatrics, kansai medical university, osaka, japanسازمان اصلی تایید شده: 0 دانشگاه های خارج از کشور

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Serum brain natriuretic peptide in children with Kawasaki disease.

BACKGROUND Kawasaki disease (KD) is a common cause of acquired heart disease in children. Recent studies have focused on the biochemical markers of the myocardium, their high sensitivity and specificity and significance in the diagnosis of KD. This study aimed to determine the serum level of brain natriuretic peptide (BNP) and its relation with the heart function of children with KD and to expl...

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N-terminal pro-brain natriuretic Peptide as a useful diagnostic marker of acute Kawasaki disease in children.

BACKGROUND Serum N-terminal pro-brain natriuretic peptide (NTproBNP) is often elevated in patients with acute Kawasaki disease (KD), but the NTproBNP level in normal children is higher than in adults. Thus, characterization of the normal levels and cut-off values of NTproBNP according to age is warranted for proper diagnosis of acute KD in children. METHODS AND RESULTS Six hundred and fifty-f...

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Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.

Using a specific radioimmunoassay for human brain natriuretic peptide (hBNP) with a monoclonal antibody, we have investigated its synthesis, secretion, and clearance in comparison with those of atrial natriuretic peptide (ANP) in normal subjects and patients with congestive heart failure (CHF). Mean BNP-like immunoreactivity (-LI) levels in normal atrium and ventricle were 250 and 18 pmol/g, re...

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Age-adjusted plasma N-terminal pro-brain natriuretic peptide level in Kawasaki disease

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Evaluation of Serum Levels of N-terminal Pro Brain Natriuretic Peptide and Atrial Natriuretic Peptide in Neonates with Respiratory Distress

Background: Acute respiratory distress (ARD) is a critical respiratory failure due to lung injury of neonates leading to the clinical appearance of poor lung compliance. The aimed of the study was to evaluate the diagnostic values in differentiating respiratory from heart diseases with using of N-terminal pro brain natriuretic peptide (NT-pro BNP) and Atrial natriuretic peptide(ANP) in neonates...

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Clinical characteristics and serum N-terminal pro-brain natriuretic peptide as a diagnostic marker of Kawasaki disease in infants younger than 3 months of age

PURPOSE The incidence of Kawasaki disease (KD) is rare in young infants (less than 3 months of age), who present with only a few symptoms that fulfill the clinical diagnostic criteria. The diagnosis for KD can therefore be delayed, leading to a high risk of cardiac complications. We examined the clinical characteristics and measured the serum levels of N-terminal pro-brain natriuretic peptide (...

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عنوان ژورنال:
journal of comprehensive pediatrics

جلد ۵، شماره ۴، صفحات ۰-۰

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